Synthetic methanotrophic and methylotrophic microorganism and method thereof
AssigneeIndustrial Microbes, Inc.
InventorsNoah Helman, Elizabeth Clarke, Derek Greenfield
Life of this patent
Estimating the term…
Abstract
Provided herein are non-naturally occurring microbial organisms comprising a methane-oxidizing metabolic pathway. The invention additionally comprises non-naturally occurring microbial organisms comprising pathways for the production of chemicals. The invention additionally provides methods for using said organisms for the production of chemicals.
Claims5
A synthetic microorganism of Escherichia coli comprising one or more genetic modifications encoding a soluble methane monooxygenase that allows said Escherichia coli to oxidize methane, wherein the one or more genetic modifications comprises the genes mmoB, mmoC, mmoX, mmoY, and mmoZ and the one or more genetic modifications additionally comprises one or more exogenous polynucleotides encoding exogenous expression of one or more protein-folding chaperones.
Dependencies are inferred from the claim text.