System and method for statistical iterative reconstruction and material decomposition

A system, comprising:

• a noise correction platform configured to:
• generate a measured sinogram based on projection data corresponding to an object to be reconstructed;
• formulate a forward model, wherein the forward model is representative of one or more characteristics of an imaging system;
• generate an estimated sinogram based on an estimated image, the forward model, or both the estimated image and the forward model;
• formulate a statistical model based on at least one of the pile-up characteristics and dead time characteristics of a detector of the imaging system;
• determine an update corresponding to the estimated image based on the statistical model and the estimated sinogram;
• update the estimated image based on the determined update to generate an updated image of the object;
• and
• output a final image of the object.

An imaging system for imaging an object to be reconstructed, the system comprising:

• an acquisition subsystem configured to acquire projection data corresponding to the object;
• a processing subsystem in operative association with the acquisition subsystem and comprising a noise correction platform, wherein the noise correction platform is configured to:
• generate a measured sinogram based on the projection data corresponding to the object;
• formulate a forward model, wherein the forward model is representative of a characteristic of the imaging system;
• generate an estimated sinogram based on an estimated image, the forward model, or both the estimated image and the forward model;
• formulate a statistical model based on at least one of pile-up characteristics and dead time characteristics of a detector of the imaging system;
• determine an update corresponding to the estimated image based on the statistical model and the estimated sinogram;
• update the estimated image based on the determined update to generate an updated image of the object;
• output a final image of the object;
• and
• a display configured to visualize at least one of the final image, the updated image, the measured sinogram, the estimated sinogram.