# US 10,670,545 B2 · System and method for cabinet x-ray systems with camera > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,670,545 B2 - Document ID: US10670545B2 - Status: Granted - Kind: B2 - Application number: 16/282,914 - Filed: 2019-02-22 - Published: 2019-06-20 - Granted: 2020-06-02 - Earliest claimed: 2017-03-27 - Assignees: KUB Technologies Inc. - Applicants: KUB Technologies, Inc. - Inventors: Vikram Butani; Yan Chen; Edwin Divakaran Maria-Selvaraj; Chester Lowe; Roberto Velasco - Web page: https://patentgrep.com/patent/US10670545B2 ## CPC - G01N 23/044: using laminography or tomosynthesis - A61B 6/025: {Tomosynthesis} - A61B 6/42: Arrangements for detecting radiation specially adapted for radiation diagnosis - A61B 6/4208: {characterised by using a particular type of detector} - A61B 6/4258: {for detecting non x-ray radiation, e.g. gamma radiation (A61B6/037 takes precedence)} - A61B 6/44: {Constructional features of apparatus for radiation diagnosis} - A61B 6/4417: {related to combined acquisition of different diagnostic modalities} - A61B 6/4429: {related to the mounting of source units and detector units} - A61B 6/4435: {the source unit and the detector unit being coupled by a rigid structure} - A61B 6/4452: {the source unit and the detector unit being able to move relative to each other} - A61B 6/4458: {the source unit or the detector unit being attached to robotic arms} - A61B 6/4464: {the source unit or the detector unit being mounted to ceiling} - A61B 6/502: {for diagnosis of breast, i.e. mammography} - A61B 6/508: {for non-human patients} - G01N 23/04: and forming images of the material - G06T 12/20: Inverse problem, i.e. transformations from projection space into object space - G01N 2223/401: image processing - G01N 2223/612: biological material - G01N 2223/6123: bone mineral - G01N 2223/6126: tissue - G06T 2210/41: Medical - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL ## Abstract The present disclosure relates to the field of a cabinet x-ray incorporating an x-ray tube, an x-ray detector, and a real-time camera, either high definition or standard resolution, for the production of organic and non-organic images. The computing device can receive video data from the camera and the x-ray detector and determines, based on the video data, an overlay of the captured x-ray image with the captured real-time image or display images adjacently i.e. Picture-In-Picture (PIP). In particular, the disclosure relates to a system and method with corresponding apparatus for capturing a real-time image simultaneously with the x-ray image allowing a cabinet x-ray unit to attain and optimize images with exact orientation of the 2 images. ## Claims ### Claim 1 A cabinet x-ray and optical camera system for obtaining projection x-ray images and optical images of a specimen, the cabinet x-ray and optical camera system comprising: a cabinet defining an interior chamber; a display; an x-ray system including: an x-ray source; an x-ray detector; and a specimen platform; an optical camera configured to capture an optical image of the specimen; and a controller configured to: selectively energize the x-ray source to emit x-rays through the specimen to the x-ray detector; control the x-ray detector to collect a projection x-ray image of the specimen when the x-ray source is energized; selectively display the projection x-ray image on the display; control the optical camera to capture and collect the optical image of the specimen; and selectively display the optical image on the display. ### Claim 2 (depends on 1) The cabinet x-ray and optical camera system of claim 1, wherein the cabinet comprises a walled enclosure surrounding the interior chamber, a door configured to cover the interior chamber and a sampling chamber within the interior chamber for containing the specimen. ### Claim 3 (depends on 1) The cabinet x-ray and optical camera system of claim 1, wherein the specimen platform is configured for excised tissue, organ, or bone specimens. ### Claim 4 (depends on 1) The cabinet x-ray and optical camera system of claim 1, wherein the specimen platform is configured for any organic or inorganic specimen that fits inside the interior chamber. ### Claim 5 (depends on 1) The cabinet x-ray and optical camera system of claim 1, wherein the specimen platform having a protective cover of and in physical contact with the x-ray detector; wherein the cabinet x-ray and optical camera system further comprises: a motion control mechanism configured for moving the x-ray source to or along a plurality of positions within the interior chamber relative to the specimen disposed on the specimen platform; and a controller further configured to: selectively energize the x-ray source to emit x-rays through the specimen to the x-ray detector at selected positions of the x-ray source relative to the specimen such that an isocenter of the emitted x-rays at the selected positions is located at a surface of the x-ray detector; control the x-ray detector to collect projection x-ray images of the specimen when the x-ray source is energized at the selected positions, wherein one of the projection x-ray images is a two-dimensional x-ray image taken at standard imaging angle of approximately 0°; create a tomosynthetic x-ray image reconstructed from a collection of projection x-ray images; process the collection of the projection x-ray images in the controller to create one or more reconstructed tomosynthetic x-ray images representing a volume of the specimen and relating to one or more image planes that are selectively the same or different from that of the two-dimensional x-ray image; and selectively display the two-dimensional x-ray image and the one or more reconstructed tomosynthetic x-ray images. ### Claim 6 (depends on 1) The cabinet x-ray and optical camera system of claim 1, wherein the controller is configured to control the x-ray detector to collect a projection x-ray image of the specimen when the x-ray source is energized and control the optical camera to capture and collect the optical image of the specimen such that the projection x-ray image and optical image are collected at substantially the same time. ### Claim 7 (depends on 1) The cabinet x-ray and optical camera system of claim 1, wherein an orientation of the specimen in the projection x-ray image and the optical image are substantially the same. ### Claim 8 (depends on 1) The cabinet x-ray and optical camera system of claim 1, wherein the controller is configured to selectively display the projection x-ray image and the optical image on the display simultaneously side-by-side or picture-in-a-picture. ### Claim 9 (depends on 1) The cabinet x-ray and optical camera system of claim 1, wherein the controller is configured to selectively display the projection x-ray image and the optical image on the display overlaid. ### Claim 10 A cabinet x-ray and optical camera system for obtaining x-ray images, projection x-ray images, reconstructed tomosynthetic x-ray images, and optical images of a specimen, the cabinet x-ray and optical camera system comprising: a cabinet defining an interior chamber and an equipment enclosure; a display; an x-ray system including: an x-ray source positioned in the interior chamber; an x-ray detector positioned in the interior chamber; a specimen platform positioned in the interior chamber and which comprises a protective cover of and in physical contact with the x-ray detector; and a motion control mechanism positioned in the interior chamber and configured for moving the x-ray source to or along a plurality of positions within the interior chamber relative to the specimen disposed on the specimen platform; an optical camera positioned in the interior chamber configured to capture an optical image of the specimen; and a controller positioned in the equipment enclosure and configured to: selectively energize the x-ray source to emit x-rays through the specimen to the x-ray detector at selected positions of the x-ray source relative to the specimen such that an isocenter of the emitted x-rays at the selected positions is located at a surface of the x-ray detector; control the x-ray detector to collect projection x-ray images of the specimen when the x-ray source is energized at the selected positions, wherein one of the projection x-ray images is a two-dimensional x-ray image taken at standard imaging angle of approximately 0°; create a tomosynthetic x-ray image reconstructed from a collection of projection x-ray images; process the collection of the projection x-ray images in the controller to create one or more reconstructed tomosynthetic x-ray images representing a volume of the specimen and relating to one or more image planes that are selectively the same or different from that of the two-dimensional x-ray image; control the optical camera to capture and collect the optical image of the specimen; and selectively display at least one of the two-dimensional x-ray image, the one or more reconstructed tomosynthetic x-ray images, and the optical image on the display. ### Claim 11 (depends on 10) The cabinet x-ray and optical camera system of claim 10, wherein the cabinet comprises a walled enclosure surrounding the interior chamber, a door configured to cover the interior chamber, and a sampling chamber within the interior chamber for containing the specimen. ### Claim 12 (depends on 10) The cabinet x-ray and optical camera system of claim 10, wherein the specimen platform is configured for excised tissue, organ, or bone specimens. ### Claim 13 (depends on 10) The cabinet x-ray and optical camera system of claim 10, wherein the specimen platform is configured for any organic or inorganic specimen that fits inside the interior chamber. ### Claim 14 (depends on 10) The cabinet x-ray and optical camera system of claim 10, wherein the controller is configured to control the x-ray detector to collect projection x-ray images of the specimen when the x-ray source is energized and control the optical camera to capture and collect the optical image of the specimen such that the optical image is collected at substantially the same time as at least one of the projection x-ray images. ### Claim 15 (depends on 10) The cabinet x-ray and optical camera system of claim 10, wherein an orientation of the specimen in the two-dimensional x-ray image, the one or more reconstructed tomosynthetic x-ray images, and the optical image are substantially the same. ### Claim 16 A method for obtaining a projection x-ray image and an optical image of a specimen in a cabinet x-ray and optical image system, processing and displaying the projection x-ray image and optical image of the specimen, wherein the cabinet x-ray and optical image system comprises: a cabinet defining an interior chamber; a display; an x-ray system including: an x-ray source; an x-ray detector; and a specimen platform; an optical camera configured to capture an optical image of the specimen; and a controller configured to: selectively energize the x-ray source to emit x-rays through the specimen to the x-ray detector; control the x-ray detector to collect a projection x-ray image of the specimen when the x-ray source is energized; selectively display the projection x-ray image on the display; control the optical camera to capture and collect the optical image of the specimen; and selectively display the optical image on the display, wherein the method comprises: controlling the x-ray detector to collect a projection x-ray image of the specimen when the x-ray source is energized; controlling the optical camera to capture and collect the optical image of the specimen; and selectively displaying at least one of the projection x-ray image and the optical image on the display. ### Claim 17 (depends on 16) The method of claim 16, further comprising displaying the projection x-ray image and the optical image simultaneously side-by-side or picture-in-a-picture. ### Claim 18 (depends on 16) The method of claim 16, further comprising displaying the projection x-ray image and the optical image on the display overlaid. ### Claim 19 (depends on 16) The method of claim 16, wherein the specimen platform having a protective cover of and in physical contact with the x-ray detector; wherein the cabinet x-ray and optical camera system further comprises: a motion control mechanism configured for moving the x-ray source to or along a plurality of positions within the interior chamber relative to the specimen disposed on the specimen platform; and a controller further configured to: selectively energize the x-ray source to emit x-rays through the specimen to the x-ray detector at selected positions of the x-ray source relative to the specimen such that an isocenter of the emitted x-rays at the selected positions is located at a surface of the x-ray detector; control the x-ray detector to collect projection x-ray images of the specimen when the x-ray source is energized at the selected positions, wherein one of the projection x-ray images is a two-dimensional x-ray image taken at standard imaging angle of approximately 0°; create a tomosynthetic x-ray image reconstructed from a collection of projection x-ray images; process the collection of the projection x-ray images in the controller to create one or more reconstructed tomosynthetic x-ray images representing a volume of the specimen and relating to one or more image planes that are selectively the same or different from that of the two-dimensional x-ray image; and selectively display the two-dimensional x-ray image and the one or more reconstructed tomosynthetic x-ray images, and the method further comprises: controlling the x-ray detector to collect projection x-ray images of the specimen when the x-ray source is energized at the selected positions such that the isocenter of the emitted x-rays at the selected positions is located at a surface of the x-ray detector, wherein one of the projection x-ray images is a two-dimensional x-ray image taken at standard imaging angle of approximately 0°; create a tomosynthetic x-ray image reconstructed from a collection of projection x-ray images; processing the collection of the projection x-ray images in the controller to create one or more reconstructed tomosynthetic x-ray images representing a volume of the specimen and relating to one or more image planes that are selectively the same or different from that of the two-dimensional x-ray image; and selectively displaying at least one of the one or more reconstructed tomosynthetic x-ray images on the display. ### Claim 20 (depends on 19) The method of claim 19, further comprising displaying the projection x-ray image or the one or more reconstructed tomosynthetic x-ray images and the optical image simultaneously side-by-side or picture-in-a-picture. ### Claim 21 (depends on 19) The method of claim 19, further comprising displaying the projection x-ray image or the one or more reconstructed tomosynthetic x-ray images and the optical image on the display overlaid. ### Claim 22 (depends on 16) The method of claim 16, wherein controlling the x-ray detector to collect the projection x-ray image of the specimen when the x-ray source is energized and controlling the optical camera to capture and collect the optical image of the specimen such that the projection x-ray image and optical image are collected at substantially the same time.