US 10,669,241 B2Granted

PTEN binding compounds, formulations, and uses thereof

AssigneeUniversity of South Florida

InventorsVrushank G. Davé, Jianfeng Cai

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Abstract

Described herein are compounds and formulations thereof that can bind PTEN. Also described herein are methods of using the compounds and formulations thereof that can bind PTEN. In some embodiments, the method can include administering an amount of a compound or formulation described herein to a subject in need thereof.

Claims3

Dependent claims

A compound having a structure according to Formula 1

where R1 is H,
where R2 is
where R3 is
where R4 is
or where R3 and R4 together form

2 more elements

Dependencies are inferred from the claim text.

Facts

Application: 16/265,662Filed 1 Feb 2019 · continuation
Priority: 17 Feb 2017
Published: US 2019/0161450 A130 May 2019
Granted: 2 Jun 2020
Term ends: Not estimatedThe source records don’t support an estimate.

Classification8 codes

C07D 233/74
Two oxygen atoms, e.g. hydantoin: with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
A61P 35/00
Antineoplastic agents
C07C 237/06
The carbon skeleton being acyclic and saturated: having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon…
C07C 311/33
Having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms: of a saturated carbon skeleton containing rings

Family

Application62/460,324Us provisional application · filed 17 Feb 2017
PCT/US2018/000049Parent of this continuation · filed 16 Feb 2018
US 2019/0161450 A1Pre-grant publication · published 30 May 2019
US 10,669,241 B2This patent

From the US filing history. Foreign family members aren’t listed.

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