Curcumin conjugates and methods of use thereof

A curcumin conjugate of the general formula

• wherein the dotted lines between A and C1, C1 and C2, C2 and C3 and C3 and D indicate that a single or double bond may be present, as valence permits,
• wherein the dotted lines between A and M, and D and Q indicate that a single bond or no bond may be present, as valence permit,
• wherein C1, C2, and C3 are carbon atoms,
• wherein A and D are oxygen atoms,
• wherein M and Q are independently absent, or hydrogen, as valence permits,
• wherein R2 and R3 can be one or more amino acids or salts thereof, nucleic acids, lipids, polysaccharides, polymers, substituted or unsubstituted alkyl groups, alkenyl groups, alkynyl groups, aryl groups, heteroaryl groups, or other organic groups containing between C1 and C10 carbon atoms, inclusive,
• wherein R1 and R4 can be carboxybenzyl (Cbz), or fluorenylmethyloxycarbonyl (FMOC), and
• wherein L1 and L2 can be independently absent, substituted or unsubstituted alkyl groups, alkenyl groups, alkynyl groups, aryl groups, heteroaryl groups, or other organic groups containing between C1 and C10 carbon atoms, inclusive or a combination thereof or pharmaceutically acceptable salt(s), polymorph(s), solvent(s), hydrate(s), crystal forms, and/or enantiomer(s) thereof.