Bacterial compositions for prophylaxis and treatment of degenerative disease
AssigneeUAS Laboratories LLC
InventorsSatya Prakash, Mitchell Lawrence Jones, Christopher Martoni
Life of this patent
Estimating the term…
Abstract
The disclosure provides an oral composition for reducing serum cholesterol, serum lipids, body fat, or atherogenic index or for prophylaxis or treatment of atherosclerosis, cardiovascular or cerebrovascular diseases, comprising a highly bsh active bacteria, isolate or supernatant thereof; wherein the highly bsh active bacteria degrades >50 μmol glycodeoxycholic acid (GDCA)/gram/hour and >2 μmol taurodeoxycholic acid (TDCA)/gram/hour when measured over 1 hour and 5 hours, respectively, or degrades >65 μmol GDCA/g/hr and >7 μmol TDCA/g/hr when measured over 30 minutes.
Claims22
A bile salt hydrolase (BSH) active bacteria, comprising a first BSH activity that results from growth in an optimized plurality of growth medium components, wherein said first BSH activity is between 6.1 and 113.6 fold higher than a second BSH activity that results from the growth of said BSH active bacteria in de Man, Rogosa, Sharpe (MRS) medium.
Dependencies are inferred from the claim text.