Methods and compositions for extending lifespan
AssigneeLongevica Theraputics Inc.
InventorsAlexey Ryazanov, Alexander Chikunov, Yuriy Shymkiv
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Abstract
The present invention relates to methods for attenuating aging, of health maintenance, and/or treating, or delaying the onset of, an age-related condition or disorder, in a subject comprising administering to the subject an effective amount of (a) one or more compounds that sustain pharmacological activation of xenobiotic metabolism or induce fermentation by gut bacteria to produce substances that activate xenobiotic metabolism enzymes and/or stimulate xenobiotic excretion and (b) one or more chelators. A further aspect of the invention is a composition comprising (a) and (b).
Claims11
A method of prolonging the lifespan of a subject, the method comprising administering to the subject an effective amount of:
- (a) one or more compounds selected from:
- (i) clofibrate, and (ii) inulin;
- and
- (b) diethylenetriaminepentaacetic acid (DTPA)
- wherein the lifespan to the subject is prolonged relative to the lifespan of the subject in the absence of the administration.
Dependencies are inferred from the claim text.