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US 10,650,532 B2Granted
Single- and multi-modality alignment of medical images in the presence of non-rigid deformations using phase correlation
AssigneeViewRay Technologies, Inc.
InventorsGeorgi Gerganov, Iwan Kawrykow
Life of this patent
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Abstract
A phase correlation method (PCM) can be used for translational and/or rotational alignment of 3D medical images even in the presence of non-rigid deformations between first and second images of a registered volume of a patient.
Claims18
A computer program product comprising a non-transitory machine-readable medium storing instructions which, when executed by at least one programmable processor, cause the at least one programmable processor to perform operations comprising:
- receiving a first medical image of a patient taken at a first time and at a first position and a second medical image of the patient taken at a second time and at a second position, the first medical image and the second medical image different due to a deformation present in the second medical image;
- comparing the first medical image and the second medical image using a phase correlation method, the comparing comprising:
- calculating an inverse Fourier transform of a cross-power spectrum of the first medical image and the second medical image, the inverse Fourier transform having a peak spread around neighboring voxels due to the deformation;
- and
- calculating a displacement of the peak based at least partially on the intensities of the neighboring voxels;
- determining, based on the displacement, a change to at least one of a physical location and a physical orientation of the patient;
- and
- correcting, based on the determined change, the second position of the patient to more closely conform to the first position of the patient.
5 more elements
A system comprising:
- at least one programmable processor;
- and
- a non-transitory machine-readable medium storing instructions which, when executed by the at least one programmable processor, cause the at least one programmable processor to perform operations comprising:
- receiving a first medical image of a patient taken at a first time and at a first position and a second medical image of the patient taken at a second time and at a second position, the first medical image and the second medical image different due to a deformation present in the second medical image;
- comparing the first medical image and the second medical image using a phase correlation method, the comparing comprising:
- calculating an inverse Fourier transform of a cross-power spectrum of the first medical image and the second medical image, the inverse Fourier transform having a peak spread around neighboring voxels due to the deformation;
- and
- calculating a displacement of the peak based at least partially on the intensities of the neighboring voxels;
- determining, based on the displacement, a change to at least one of a physical location and a physical orientation of the patient;
- and
- correcting, based on the determined change, the second position of the patient to more closely conform to the first position of the patient.
8 more elements
Dependencies are inferred from the claim text.