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US 10,649,198 B2Granted
Sample processing and analysis methods and apparatus
AssigneeBattelle Memorial Institute
InventorsMicah D. Miller, James Preston McKinley
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Abstract
Sample handling, processing and analysis methods and apparatus are described. According to one aspect, a sample processing method includes providing a sample, providing a reference frame which comprises a plurality of markers arranged in a predefined pattern, wherein individual ones of the markers are uniquely identifiable from others of the markers, and associating the reference frame comprising the markers with the sample. The markers are amenable to human or machine reading and for computational manipulation in some examples.
Claims30
A sample processing method comprising:
- providing a physical sample;
- associating a reference frame with the sample, wherein the reference frame comprises a plurality of markers arranged in a predefined pattern and wherein individual ones of the markers are uniquely identifiable from others of the markers;
- identifying a location of a target of the sample with respect to at least one of the markers;
- storing the location of the target with respect to the at least one marker;
- after the storing, locating the target within the sample using the stored location and the at least one marker;
- and
- wherein the physical distance between the target and the at least one marker changes after the storing and before the locating.
4 more elements
Dependencies are inferred from the claim text.