Free-breathing 3D body diffusion imaging using motion-compensated diffusion preparation and motion robust readout

A computer program product for free breathing three dimensional diffusion imaging, the computer program product comprising a non-transitory computer readable storage medium having program instructions embodied therewith, the program instructions executable by a processor to cause the processor to:

• initiate a motion robust diffusion/T2 preparation process comprising:
• generate diffusion contrast;
• and
• adjust one or more of amplitude, duration, and polarity to null a first order moment;
• apply a motion robust non-Cartesian k-space ordering, comprising:
• acquire a radial/spiral view for all members of a plurality of partitions in a partition-encoding direction;
• increase an azimuthal angle until a complete set of radial/spiral views are sampled;
• and
• apply diffusion gradients along each of three axis simultaneously;
• and
• calculate an apparent diffusion coefficient map.

A system for 3D motion correction for free breathing three dimensional diffusion imaging, the system comprising:

• a medical imaging device comprising:
• a k-space component processor configured to:
• initiate a motion robust diffusion/T2 preparation process comprising:
• generate diffusion contrast;
• and
• adjust one or more of amplitude, duration, and polarity to null a first or second order moment;
• and
• an image data processor configured to:
• apply a motion robust non-Cartesian ordering, comprising:
• acquire a radial/spiral view for all members of a plurality of partitions in a partition-encoding direction;
• increase an azimuthal angle until a complete set of radial/spiral views are sampled;
• and
• apply diffusion gradients along each of three axis simultaneously;
• and
• calculate an apparent diffusion coefficient map.