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US 10,647,954 B1Granted
Dendritic cell generating apparatus and method
AssigneeFlaskworks, LLC
InventorAndrew Kozbial
Life of this patent
Estimating the term…
Abstract
A cell culture cartridge is provided comprising a plurality of zones geometrically configured to provide for symmetrical fluid flow with each of the plurality of zones to avoid dead areas in flow within each of the plurality of zones. In certain embodiments, at least eight inlets are provided, with an inlet positioned at each corner of the cell culture cartridge. In certain embodiments, a shared outlet is positioned on a top surface of the cell culture cartridge.
Claims21
A cell culture cartridge comprising:
- a top surface comprising a plurality of inlets and a plurality of corners, wherein each of the plurality of inlets is positioned at one of the plurality of corners;
- a bottom surface, wherein the bottom surface and the top surface together, at least in part, define a plurality of zones, each zone comprising one of the corners and one of the inlets, and wherein the zones converge at a center of the top surface;
- and
- an outlet positioned at the center of the top surface;
- wherein each of the plurality of zones, due at least in part to the position of the inlet in each zone relative to the outlet provide for symmetrical fluid flow between its respective inlet and the outlet to avoid dead areas in flow within each of the plurality of zones.
2 more elements
A cell culture system comprising:
- a cell culture cartridge comprising:
- a top surface comprising a plurality of inlets and a plurality of corners, wherein each of the plurality of inlets is positioned at one of the plurality of corners;
- a bottom surface, wherein the bottom surface and the top surface together, at least in part, define a plurality of zones, each zone comprising one of the corners and one of the inlets, and wherein the zones converge at a center of the top surface;
- and
- an outlet positioned at the center of the top surface;
- wherein each of the plurality of zones, due at least in part to the position of the inlet in each zone relative to the outlet provide for symmetrical fluid flow between its respective inlet and the outlet to avoid dead areas in flow within each of the plurality of zones;
- and
- one or more pumps operably associated with the cell culture chamber.
5 more elements
Dependencies are inferred from the claim text.