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US 10,647,725 B2Granted
Anti-infective 2-aminothiophenes
AssigneesThe University of Toledo, Colorado State University Research Foundation
InventorsSteven Sucheck, Sandeep Thanna, Richard Slayden
Life of this patent
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Abstract
2-Aminothiophene derivatives, uses of the same, and methods of making the same, are described.
Claims12
A compound of Formula III:
- wherein R5 is NEt, R6 is COPhF5, and R7 is C1-C8 alkyl, C1-C8 alkoxy, or C1-C8 alkylamino.
A compound of Formula 506:
A compound of Formula 507:
A compound of Formula 508:
A compound of Formula 509:
A compound of Formula 510:
A compound of Formula 511:
A compound of Formula 512:
A compound of Formula 513:
A compound of Formula 514:
A compound of Formula 515:
A compound of Formula V:
- wherein:
- R1 is H, or substituted or unsubstituted C1-C8 acyl, C1-C8 alkyl, C1-C8 aminoalkyl, C1-C8 alkenyl, or Ph;
- and
- R2 is a substituted or substituted tetrazole, oxadiazole, thiadiazole, thiadiazole ketone, oxadiazolethione, amide, acylurea, or oxadiazole ketone;
- and salts, stereoisomers, racemates, hydrates, solvates, prodrugs, and polymorphs thereof.
2 more elements
Dependencies are inferred from the claim text.