Dihydroisoquinoline compound

A compound of general formula I:

• wherein:
• R is any one of hydrogen and C1-6 alkyl;
• R1 is any one of hydrogen, deuterium, halogen, C1-6 alkyl, C1-6 alkylamino, and C1-6 alkoxy;
• R2 is any one of hydrogen, deuterium, halogen, C1-6 alkyl, C1-6 alkyl substituted with at least one fluorine, C3-7 cycloalkyl, C1-6 alkylamino, C1-6 alkoxy, and heterocycloalkyl;
• Ar is any one of phenyl, thienyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, pyridin-2(1H)-keto, pyridin-4(1H)-keto, pyrrolyl, pyrazolyl, thiazolyl, 1, 2, 3-triazolyl, 1, 2, 4-triazolyl, imidazolyl, tetrazolyl, isothiazolyl, oxazolyl, isoxazolyl, thiadiazolyl, oxadiazolyl, naphthyl, benzothiophenyl, indolyl, benzimidazolyl, benzothiazolyl, benzofuryl, quinolyl, isoquinolyl, and quinazolinyl;
• R3 is any one of hydrogen, deuterium, halogen, cyano, C1-6 alkyl, C3-7 cycloalkyl, C1-6 alkylamino, C1-6 alkoxy, and heterocycloalkyl;
• R4 is any one of hydrogen, deuterium, and C1-6 alkyl;
• R5 is any one of hydrogen, deuterium, C1-6 alkyl, C1-6 alkyl substituted with at least one fluorine, and C3-7 cycloalkyl,
• an enantiomer, a diastereomer, a solvate, a hydrate, a prodrug, a stable isotope derivative or a pharmaceutically acceptable salt thereof.