Systems, devices, and associated methods for treating patients via renal neuromodulation to reduce a risk of developing cognitive impairment

A method for decreasing a human patient's risk of developing dementia, the method comprising:

• obtain, using a processor, user input that indicates one or more patient factors;
• determining, using the processor, a dementia risk score that assesses an amount of risk associated with the development of dementia in a human patient based on the user input that indicates the one or more patient factors;
• determining, using the processor, that the dementia risk score is greater than a threshold dementia risk score that represents an upper limit of an acceptable risk of dementia;
• intravascularly positioning a catheter carrying a neuromodulation assembly within a renal blood vessel and adjacent to renal nerves innervating a kidney of the human patient;
• delivering, using an energy source, energy to the renal nerves via the neuromodulation assembly to attenuate neural traffic along the renal nerves, decrease the dementia risk score and reduce a probability of dementia developing in the human patient;
• determining, using the processor, a post-neuromodulation dementia risk score that assesses the amount of risk associated with the development of dementia in the human patient after delivering the energy to the renal nerves;
• and
• removing the catheter and neuromodulation assembly from the human patient after treatment and when the post-neuromodulation dementia risk score is less than the dementia risk score.