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US 10,646,617 B2Granted
Chemical gradients
AssigneeBoard of Regents, The University of Texas System
InventorsMario I. Romero-Ortega, Parisa Lotfi, Benjamin R. Johnston, Swarupnarayan Dash, Joselito Razal, Gordon Wallace
Life of this patent
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Abstract
In one aspect, apparatuses for providing chemical gradients are described herein. In some embodiments, an apparatus described herein comprises a conduit having a first end and a second end, one or more microchannels disposed in the conduit and extending from the first end toward the second end, and a fiber coiled around the exterior of at least one microchannel, wherein the fiber comprises an active agent that is operable to diffuse into the interior of the microchannel.
Claims13
A composition comprising:
- a first matrix comprising an active agent at a first concentration;
- and
- a second matrix comprising the active agent at a second concentration differing from the first concentration,
- wherein the first matrix and the second matrix are arranged in space to provide a concentration gradient of the active agent,
- wherein the concentration gradient is a linear concentration gradient extending along a length of the composition, wherein the first matrix and second matrix are disposed in a conduit, and
- wherein the first matrix and/or the second matrix is formed from a hydrogel.
3 more elements
Dependencies are inferred from the claim text.