Methods for treating and diagnosing blinding eye diseases
AssigneeTranslatum Medicus Inc.
InventorShelley Romayne Boyd
Life of this patent
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Abstract
This invention relates to, in part, methods and compositions that are useful for the diagnosis, treatment, or prevention of a blinding eye disease, including in the discovery of drugs that are efficacious against these diseases. Diseases include, for example, age related macular degeneration and reticular pseudodrusen disease, and the methods described herein include, for example, the method named delayed near infrared analysis (DNIRA).
Claims16
A method for modulating macrophage polarization in RPE cells in the eye of a subject in need thereof, comprising administering to said subject an effective amount of a compound of Formula I:
- or a pharmaceutically acceptable salt thereof, wherein:
- each of R1 and R2 is independently H or a C1-C6 alkyl and
- R3 is H or a C1-C6 alkyl.
Dependencies are inferred from the claim text.