Treatment of allergic rhinitis using a combination of mometasone and olopatadine
AssigneeGlenmark Specialty S.A.
InventorsNeelima Khairatkar-Joshi, Abhay Kulkarni, Dinesh Pradeep Wale, Vikram Mansingh Bhosale, Piyush Agarwal, Patrick Keohane, Sudeesh K. Tantry, Chad Oh
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Abstract
The present patent application relates to a method of treating allergic rhinitis in a subject (preferably a human) by administering a combination of mometasone or its salt and olopatadine or its salt.
Claims15
A method of treating one or more symptoms associated with allergic rhinitis in a human subject in need thereof comprising nasally administering to the human subject a fixed-dose pharmaceutical composition comprising mometasone furoate and olopatadine hydrochloride, wherein (i) the composition is nasally administered as 2 sprays per nostril of the human subject twice daily, (ii) each spray of the composition comprises about 25 mcg mometasone furoate and olopatadine hydrochloride equivalent to about 600 mcg olopatadine, and (iii) the twice daily administration of the pharmaceutical composition provides a faster onset of action than twice daily administration of olopatadine hydrochloride equivalent to about 1200 mcg olopatadine per nostril alone.
A method of treating one or more symptoms associated with seasonal allergic rhinitis in a human subject in need thereof comprising nasally administering to the human subject a fixed-dose pharmaceutical composition in the form of a suspension comprising mometasone furoate in particulate form and olopatadine hydrochloride in solution, wherein (i) the composition is administered as 2 sprays per nostril of the human subject, twice daily, (ii) each spray of the composition comprises about 25 mcg mometasone furoate and about 665 mcg olopatadine hydrochloride, and (iii) the twice daily administration of the pharmaceutical composition provides a faster onset of action than twice daily administration of olopatadine hydrochloride equivalent to about 1200 mcg olopatadine alone.
Dependencies are inferred from the claim text.