Joint application of statin and adrenocortical hormone for treating chronic subdural hematoma
AssigneesJianning Zhang, Rongcai Jiang, Dong Wang
InventorsJianning Zhang, Rongcai Jiang, Dong Wang, Wei Quan
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Abstract
The present invention provides joint use of stain and adrenocortical hormone for preparing a pharmaceutical product for the treatment of chronic subdural hematoma. The pharmaceutical product according to the present invention is capable of accelerating hematoma absorption and improving a therapeutic effect of single oral administration of a statin-based pharmaceutical product, and the dose of the adrenocortical hormone-based pharmaceutical product used is 1/10 of the dose used in a large-dose hormonal therapy.
Claims2
A method for treatment of chronic subdural hematoma, comprising administering an effective amount of a drug to a subject of the treatment, wherein said drug comprises a statin and an adrenocortical hormone, wherein the statin is atorvastatin and the adrenocortical hormone is dexamethasone;
- wherein the administration regimen of the atorvastatin and the dexamethasone is as follows:
- in the first week:
- atorvastatin 10 m+dexamethasone 0.75 mg, 3 times per day;
- in the second to third weeks:
- atorvastatin 10 and dexamethasone 0.75 mg, 2 times per day;
- and
- in the fourth week:
- atorvastatin 10 mg+dexamethasone 0.75 mg, 1 time per day.
Dependencies are inferred from the claim text.