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US 10,646,470 B2Granted
Uses of indolinone compounds
AssigneeOncternal Therapeutics, Inc.
InventorsBrian Lannutti, Katayoun Jessen, James Bradley Breitmeyer
Life of this patent
Estimating the term…
Abstract
Methods and compositions for treating acute myeloid leukemia and diffuse large B cell lymphoma using combinations of venetoclax and indolinone derivatives are provided.
Claims8
A method for inducing apoptosis in a lymphocyte produced in mantle cell lymphoma or diffuse large B cell lymphoma, comprising contacting the cell with an effective amount of:
- lenalidomide;
- and
- a compound having a structure:
- or a stereoisomer, a pharmaceutically acceptable salt, or solvate thereof.
1 more element
A pharmaceutical composition, comprising:
- lenalidomide;
- and
- a compound having a structure:
- or a stereoisomer, a pharmaceutically acceptable salt, or solvate thereof.
1 more element
Dependencies are inferred from the claim text.