Delivery system comprising a core and a digestible polymer shell
AssigneeSociete des Produits Nestle S.A.
InventorsTimothy James Wooster, Laurence Donato-Capel, Anwesha Sarkar, Simone Acquistapace
Life of this patent
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Abstract
A delivery vehicle with a core surrounded by a digestible polymer shell having a melting and/or softening point above the body temperature of an animal or human, and where the core has a lipid and/or lipophilic active ingredient dispersed in a continuous polymer matrix. The delivery vehicle can be used to release lipid and/or lipophilic active ingredients, such as pharmaceuticals, nutraceuticals, supplements, traditional/herbal medicine, or combinations thereof, after a predetermined lag time following ingestion.
Claims23
A delivery vehicle comprising a core surrounded by a digestible polymer shell having a melting and/or softening point above the body temperature of an animal or human, wherein the core comprises a lipid and/or lipophilic active ingredient dispersed in a continuous polymer matrix, and wherein the digestible polymer comprised within the digestible polymer shell is a cross linked digestible biopolymer.
A delivery vehicle comprising a core surrounded by a digestible polymer shell having a melting and/or softening point above the body temperature of an animal or human,
- wherein the core comprises a lipid and/or lipophilic active ingredient dispersed in a continuous polymer matrix,
- wherein the digestible polymer comprised within the digestible polymer shell is a cross linked digestible biopolymer, and
- wherein the lipid and/or lipophilic active ingredient is selected from the group consisting of:
- triglycerides, phospholipids, diglycerides, monoglycerides, ceramides, glycolipids and sphingolipids, fish oil, petroselinic acid, eicosapentaenoic acid, carotenoids, phytosterols, phytosterol esters, polyphenols, cholesterol, cholesterol esters, retinol, retinol ester, and combinations thereof.
A delivery vehicle comprising a core surrounded by a digestible polymer shell having a melting and/or softening point above the body temperature of an animal or human,
- wherein the core comprises a lipid and/or lipophilic active ingredient dispersed in a continuous polymer matrix,
- wherein the digestible polymer comprised within the digestible polymer shell is a cross linked digestible biopolymer, and
- wherein the core contains an emulsifier.
A delivery vehicle comprising a core surrounded by a digestible polymer shell having a melting and/or softening point above the body temperature of an animal or human,
- wherein the core comprises a lipid and/or lipophilic active ingredient dispersed in a continuous polymer matrix,
- wherein the digestible polymer comprised within the digestible polymer shell is a cross linked digestible biopolymer, and
- wherein the digestible polymer shell has an average mesh/pore size of <50 nm.
A delivery vehicle comprising a core surrounded by a digestible polymer shell having a melting and/or softening point above the body temperature of an animal or human,
- wherein the core comprises a lipid and/or lipophilic active ingredient dispersed in a continuous polymer matrix,
- wherein the digestible polymer comprised within the digestible polymer shell is a cross linked digestible biopolymer, and
- wherein the core comprises a weighting agent and/or wherein the digestible polymer shell comprises a thickener.
A delivery vehicle comprising a core surrounded by a digestible polymer shell having a melting and/or softening point above the body temperature of a subject,
- wherein the core comprises a lipid and/or lipophilic active ingredient dispersed in a continuous polymer matrix,
- wherein the digestible polymer comprised within the digestible polymer shell is a cross linked digestible biopolymer, and
- wherein 50% or more of the lipid and/or lipophilic active ingredient is released within 45 minutes or less and/or 80% or more of the lipid and/or lipophilic active ingredient is release within 75 minutes or less following the expiry of a predetermined lag time following ingestion of said delivery vehicle by the subject.
A consumable product comprising a delivery vehicle comprising a core surrounded by a digestible polymer shell having a melting and/or softening point above the body temperature of a subject, wherein the core comprises a lipid and/or lipophilic active ingredient dispersed in a continuous polymer matrix, and wherein the digestible polymer comprised within the digestible polymer shell is a cross linked digestible biopolymer, the composition and/or consumable product is selected from the group consisting of;
- pharmaceutical products, nutraceutical products, medical foods, veterinary products including pet food and pet care products and, foodstuffs of any kind including functional foods and food supplements.
Dependencies are inferred from the claim text.