Tablet
AssigneeDrug Delivery International Ltd.
InventorsHoward Norman Ernest Stevens, Alexander Balfour Mullen, Fiona Jane MacDougall, Claire Helen Ordoyno
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Abstract
A method of forming an erodible sustained release tablet comprising the steps of:—a. mixing one or more therapeutic agents, one or more disintegrant and one or more molten wax, whilst retaining the wax in molten form; b. solidifying and granulating the mixture; c. forming a tablet by compression of the granules. The invention also relates to a sustained release tablet made according to the method.
Claims21
A method of forming an erodible sustained release tablet comprising:
- a. mixing one or more therapeutic agents, one or more disintegrants and one or more molten waxes, whilst retaining the wax in molten form to form a mixture, and wherein the one or more waxes and the one or more disintegrants are mixed in a wax:disintegrant ratio of 7:1 to 1:1.13;
- b. solidifying and granulating the mixture;
- and
- c. forming the tablet by compression of the granules, and
- wherein the therapeutic agent has a constant rate of release.
A sustained release tablet comprising a wax, a disintegrant and a therapeutic agent,
- wherein the wax substantially coats particles or agglomerates of the therapeutic agent and of the disintegrant,
- wherein the wax and the disintegrant are present in a ratio of 7:1 to 1:1.13, and
- wherein the therapeutic agent has a constant rate of release.
A sustained release tablet consisting of a wax, a disintegrant and a therapeutic agent,
- wherein the wax substantially coats particles of the therapeutic agent and of the disintegrant,
- wherein the wax and the disintegrant are present in a ratio of 7:1 to 1:1.13, and
- wherein the therapeutic agent has a constant rate of release.
Dependencies are inferred from the claim text.