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US 10,646,183 B2Granted
Detection of scar and fibrous cardiac zones
AssigneeTylerton International Inc.
InventorShlomo Ben-Haim
Life of this patent
Estimating the term…
Abstract
A method of tissue recognition of tissue type in a heart or other tissue, comprising: (i) injecting a patient with a radioactive tracer; (ii) collecting radiation emitted from cardiac tissue (iii) associating said collected radiation with a wall of the heart; and (iv) analyzing said associated radiation to recognize fibrous tissue in the heart wall. Optionally, the resolution of the association is better than 5 mm.
Claims31
A method of tissue recognition of tissue type in a heart, comprising:
- (i) providing radioactive emission data of cardiac tissue;
- (ii) associating said radioactive emission data with a wall of the heart;
- and
- (iii) analyzing said radioactive emission data associated with the wall of the heart to recognize fibrous tissue in the heart wall;
- wherein the associating comprises:
- selecting emission locations of the radioactive emission data that correspond with locations of a model of the wall of the heart, and
- reconstructing a nuclear image of radioactive emissions at locations of the heart wall, using values of emission data from the selected emission locations;
- and
- wherein the analyzing comprises:
- estimating heart wall thickness in the heart wall locations of the nuclear image,
- scaling the values of the emissions of emission data in the nuclear image, using the estimated heart wall thicknesses, to produce a wall-thickness normalized nuclear emission image of the heart wall, and
- categorizing at least one of the heart wall locations as comprising an intermixing of fibrotic tissue and living muscle, based on the wall-thickness normalized nuclear emission image of the heart wall.
9 more elements
A method of tissue recognition of tissue type in a heart, comprising:
- (i) providing radioactive emission data of cardiac tissue;
- (ii) associating said radioactive emission data with respective positions on a wall of the heart;
- (iii) analyzing said radioactive emission data associated with the wall of the heart to recognize fibrous tissue in the heart wall;
- and
- (iv) producing an image showing fibrotic areas of the heart;
- wherein the associating comprises using a model of said wall generated with thicknesses personalized for the heart.
3 more elements
A method of tissue recognition of tissue type in a heart, comprising:
- (i) providing radioactive emission data of cardiac tissue;
- (ii) associating said radioactive emission data with respective positions on a wall of the heart;
- (iii) analyzing said radioactive emission data associated with the wall of the heart to recognize fibrous tissue in the heart wall;
- and
- (iv) producing an image showing fibrotic areas of the heart;
- wherein the analyzing and the image produced differentiate non-transmural scar tissue from fibrosis.
3 more elements
Dependencies are inferred from the claim text.