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US 10,639,363 B2Granted
Cancer immunotherapy using virus particles
AssigneeCase Western Reverse University
InventorsNicole F. Steinmetz, Amy M. Wen, Steven Fiering, Patrick H. Lizotte
Life of this patent
Estimating the term…
Abstract
A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
Claims11
A method of treating cancer in a subject in need thereof, the method comprising:
- administering directly to the cancer a therapeutically effective amount of an in situ vaccine, the in situ vaccine including at least one of potato virus X, or potato virus X virus-like particles, wherein the potato virus X, and potato virus X virus-like particles are not used as a vehicle for drug or antigen delivery.
A method of treating melanoma in a subject in need thereof, the method comprising:
- administering directly to the melanoma a therapeutically effective amount of an in situ vaccine, the in situ vaccine including at least one of potato virus X, or potato virus X virus-like particles, wherein the potato virus X, and potato virus X virus-like particles are not used as a vehicle for drug or antigen delivery;
- and
- administering a therapeutically effective amount of doxorubicin to the subject, wherein the doxorubicin is not loaded on or bound to the potato virus X, or potato virus X virus-like particles.
Dependencies are inferred from the claim text.