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US 10,626,099 B2Granted
Process for preparing pleuromutilin
AssigneeCalifornia Institute of Technology
InventorsElliot P. Farney, Sean S. Feng, Sarah Reisman
Life of this patent
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Abstract
The present disclosure provides processes for preparing (+)-pleuromutilin and synthetic (+)-pleuromutilin produced therefrom. Also provided are intermediates prepared thereby and processes for preparing these intermediates.
Claims25
A process comprising:
- contacting a compound of Formula I
- with samarium(II) iodide
- in an organic solvent;
- for a time and under conditions effective to produce a compound of Formula II
- wherein R1 is H or an oxygen protecting group.
2 more elements
Dependencies are inferred from the claim text.