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AssigneeVisionTech International Limited
InventorsOlivia Yee-Yee Lam, Dominic Man-Kit Lam, Han Lei, Fong Wilson Lam
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In the invention described here, the approach is to formulate an edible vaccine based on N-terminal yeast surface display expression systems including S. cerevisiae EBY100/pYD5-VP28, S. cerevisiae EBY100/pYD5-VP28-VP24 and S. cerevisiae EBY100/pYD5-VP24 for preventing shrimps such as L. vannamei, P. monodon and M. rosenbergii species from white spot syndrome virus (WSSV) infection, suggesting that yeast surface display expression system expressing WSSV antigen has potential as a prophylactic treatment for WSSV in shrimps via oral vaccination. The technology developed in this patent application can also be used to produce edible (oral) vaccines for preventing and treating other infectious diseases in animals and human.
A composition comprising a yeast expression plasmid, pYD5, for N-terminal display surface of vp28 and vp24 envelope genes from white spot syndrome virus (WSSV) in host S. cerevisiae EBY 100 for preventing shrimps from WSSV infection.
Dependencies are inferred from the claim text.