US 10,617,749 B1Granted

Composition of matter and methods for alteration of dendritic cell metabolism to augment cancer vaccine efficacy

AssigneeDuke University

InventorsBrent Hanks, Fei Zhao

Life of this patent

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Abstract

This disclosure provides compositions of matter and methods for alteration of dendritic cell metabolism to augment cancer vaccine efficacy. The compositions and methods can involve regulation of fatty acid oxidation.

Claims13

Dependent claims

A method of treating cancer in a patient treated or being treated with a cancer vaccine, the method comprising:

inhibiting fatty acid oxidation in dendritic cells of the patient.

Dependencies are inferred from the claim text.

Facts

Application: 15/441,816Filed 24 Feb 2017 · us provisional application
Priority: 24 Feb 2016
Granted: 14 Apr 2020
Term ends: Not estimatedThe source records don’t support an estimate.

Classification19 codes

A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…
A61K 35/00
Medicinal preparations containing materials or reaction products thereof with undetermined constitution
A61K 40/19
Characterised by the cell type used: dendritic cells
A61K 40/24
Characterised by the effect or the function of the cells: antigen-presenting cells [APC]

Family

Application62/299,224Us provisional application · filed 24 Feb 2016
US 10,617,749 B1This patent

From the US filing history. Foreign family members aren’t listed.

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