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US 10,612,005 B2Granted
Modified oncolytic virus
AssigneeReplimune Limited
InventorRobert Coffin
Life of this patent
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Abstract
The present invention relates to an oncolytic virus comprising: (i) a fusogenic protein-encoding gene; and (ii) an immune stimulatory molecule-encoding gene.
Claims31
An oncolytic virus comprising:
- (i) a heterologous fusogenic protein-encoding gene;
- and (ii) an immune stimulatory molecule or an immune stimulatory molecule-encoding gene.
The virus of claims g, where the retroviral LTR is from MMLV.
Dependencies are inferred from the claim text.