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US 10,611,803 B2Granted
Desmoglein 2 (DSG2) binding proteins and uses therefor
AssigneeUniversity of Washington through its Center for Commercialization
InventorsAndre Lieber, Hongjie Wang
Life of this patent
Estimating the term…
Abstract
The present invention provides recombinant adenoviral compositions and methods for their use in treating disorders associated with epithelial tissues.
Claims15
An isolated peptide, comprising the amino sequence selected from the group consisting of
- (a)
- (SEQ ID NO:
- 5)
- TLWTGPKPEANCIIEYGKQNPDSKLTLILVKNGGIVNGYVTLMGAS
- DYVNTLFKNKNVSINVELYFDATGHILPDSSSLKTDLELKYKQTADFSAR
- GFMPSTTAYPFVLPNAGTHNENFIFGQCYYKASDGALFPLEVTVMLNKRL
- PDSRTSYVMTFLWSLNAGLAPETTQATLITSPFTFSYIREDD;
- (b)
- (SEQ ID NO:
- 6)
- TLWTGPKPEANCIIEYGKQNPDSKLTLILVKNGGIVNGYVTLMGAS
- DYVNTLFKNKNVSINVELYFDATGHILPDSSSLKTDLELEYKQTADSARG
- FMPSTTAYPFVLPNAGTHNENYIFGQCYYKASDGALFPLEVTVMLNKRLP
- DSRTSYVMTFLWSLNAGLAPETTQATLITSPFTFSYIREDD;
- (c)
- (SEQ ID NO:
- 7)
- TLWTGPKPEANCIIEYGKQNPDSKLTLILVKNGGIVNGYVTLMGAS
- DYVNTLFKNKNVSINVELYFDATGHILPDSSSLKTDLELKYKQTADFSAR
- GFMPSTTAYPFVLPNAGTHNENYIFGQCYYKASDGALFPLEVTVMLNKRL
- PDSRTSYVMTFLWSLSAGLAPETTQATLITSPFTFSYIREDD;
- (d)
- (SEQ ID NO:
- 8)
- TLWTGPKPEANCIIEYGKQNPDSKLTLILVKNGGIVNGYVTLMGAS
- DYVNTLFKNKNVSINVELYFDATGHILPDSSSLKTDLELKYKQTADFSAR
- GFMPSTTAYPFDLPNAGTHNENYIFGQCYYKASDGALFPLEVTVMLNKRL
- PDSRTSYVMTFLWSLNAGLAPETTQATLITSPFTFSYIREDD;
- (e)
- (SEQ ID NO:
- 9)
- TLWTGPKPEANCIIEYGKQNPDSKLTLILVKNGGIVNGYVTLMGASD
- YVNTLFKNKNVSINVELYFDATGHILPDSSSLKTDLEPKYKQTADFSARG
- FMPSTTAYPFVLPNAGTHNENYIFGQCYYEASDGALFPLEVTVMLNKRLP
- DSRTSYVMTFLWSLNAGLAPETTQATLITSPFTFSYIREDD;
- (f)
- (SEQ ID NO:
- 10)
- TLWTGPKPEANCIIEYGKQNPDSKLTLILVKNGGIVNGYVTLMGAS
- DYVNTLFKNKNVSINVELYFDATGHILPDSSSLKTDLELKYKQTADLSAR
- GFMPSTTAYPFVLPNAGTHNENYIFGQCYYKASDGALFPLEVTVMLNKRL
- PDSRTSYVMTFLWSLNAGLAPETTQATLITSPFTFSYIREDD;
- and
- (g)
- (SEQ ID NO:
- 11)
- TLWTGPKPEANCIIEYGKQNPDSKLTLILVKNGGIVNGYVTLMGAS
- DYVNTLFKNKNVSINVELYFDATGHILPDSSSLKTDLELKYKQTADFSAR
- GFMPSTTAYPFVLPNAGTHNGNYIFGQCYYEASDGALFPLEVTVMLNKRL
- PDSRTSYVMTFLWSLNAGLAPETTQATLITSPFTFSYIREDD.
47 more elements
Dependencies are inferred from the claim text.