Method for predicting the risk of getting cancer or diagnosing cancer in a subject
AssigneeSphingotec GmbH
InventorAndreas Bergmann
Life of this patent
Estimating the term…
Abstract
A method for predicting the risk of getting cancer in a subject that does not suffer from cancer or alternatively diagnosing cancer in a subject, where the method includes determining the level of Pro-Tachykinin, its splice variants or fragments thereof of at least 5 amino acids, where the fragments including Substance P and Neurokinin, in a bodily fluid obtained from the subject; and correlating the level of Pro-Tachykinin, its splice variants or fragments thereof with a risk for getting cancer, wherein a reduced Pro-Tachykinin level is predictive for an enhanced risk of getting cancer or alternatively diagnosing cancer wherein a reduced level is correlated with the diagnosis of cancer.
Claims27
A method for predicting the risk of getting cancer in a subject that does not suffer from cancer comprising:
- determining the level of Pro-Tachykinin in a bodily fluid sample obtained from said subject by determining the level of binding to the region of Pro-Tachykinin that consists of Pro-Tachykinin 1-37 (SEQ ID NO. 2) by measuring the level with an immunoassay having an antibody specific to binding to SEQ ID NO. 2;
- and
- correlating said level of Pro-Tachykinin with risk for getting cancer, wherein a reduced level is predictive for an enhanced risk of getting cancer and said reduced level is a level below a threshold wherein said threshold is set at 100 pmol/l or below.
Dependencies are inferred from the claim text.