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US 10,598,660 B2Granted
Application of anaplasma phagocytophilum protein APH1384
AssigneeSoochow University
InventorsHua Niu, Meiling He, Shuyan Wu
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Abstract
The present invention relates to use of an Anaplasma phagocytophilum protein APH1384 as diagnostic antigen for granulocytic anaplasmosis. The protein can remedy the drawback of missed detection of an existing diagnostic antigen P44 for granulocytic anaplasmosis, improve sensitivity of detection for granulocytic anaplasmosis, and facilitate rapid and accurate clinical diagnosis of granulocytic anaplasmosis.
Claims2
A method for diagnosing granulocytic anaplasmosis in a subject comprising:
- providing an APH1384 antigenic epitope polypeptide having an amino acid sequence shown in SEQ ID NO:
- 2;
- and
- detecting anti-APH1384 antibodies in the subject using the APH1384 antigenic epitope polypeptide as an antigen,
- wherein the anti-APH1384 antibodies are the antibodies of an Anaplasma phagocytophilum protein APH1384 in the subject.
2 more elements
Dependencies are inferred from the claim text.