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US 10,596,233 B2Granted
Use of pertussis toxin as a therapeutic agent
AssigneeDignity Health
InventorJiong Shi
Life of this patent
Estimating the term…
Abstract
The present application relates to the use of pertussis toxin, and its derivatives, analogs, salts and pharmaceutical equivalents. In one embodiment, the invention provides a method of treating or preventing a neurological disease or injury by administering pertussis toxin to the individual.
Claims11
A method of reducing migration of microglia into neurologically damaged tissue in a human subject's spinal cord, the method comprising the steps of:
- providing a composition comprising pertussis toxin (PTx) comprising subunits A and B;
- and
- reducing the migration of microglia into the neurologically damaged tissue of the human subject's spinal cord via administering a therapeutically effective dosage of the composition to the human subject, wherein the human subject has multiple sclerosis.
Dependencies are inferred from the claim text.