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US 10,595,532 B2Granted
Ophthalmic contact lens solutions containing forms of vitamin B
AssigneeFXS Ventures, LLC
InventorFrancis X. Smith
Life of this patent
Estimating the term…
Abstract
The present invention relates to improved ophthalmic solutions that employ select B vitamins; pyridoxine and its salts; and thiamine and its salts in order to more effectively preserve solutions and to reduce the degree to which cationic preservatives will deposit on contact lenses. Ophthalmic solutions are here understood to include contact lens treatment solutions, such as cleaners, soaking solutions, conditioning solutions and lens storage solutions, as well as wetting solutions and in-eye solutions for treatment of eye conditions.
Claims18
A contact lens solution comprising:
- at least 0.00001 weight percent of a cationic preservative selected from a group consisting of polyhexamethylene biguanide and polyquaternium-1;
- between 0.00001 and 10 weight percent of pantothenic acid or a salt of pantothenic acid that functions as a preservative enhancer;
- a physiologically compatible buffer selected from a group consisting of phosphate, bicarbonate, citrate, borate, ACES, BES, BICINE, BIS, BIS-Tris, BIS-Tris Propane, HEPES, HEPPS, imidazole, MES, MOPS, PIPES, TRIS, TAPS, TES, an amino acid, and Tricine;
- wherein the contact lens solution has a low chloride concentration of less than 0.1 mole percent chloride, and the combination of the cationic preservative, the preservative enhancer, and the low chloride concentration provide an enhanced preservative effect relative to a corresponding contact lens solution having a chloride concentration of more than 0.1 mole percent.
1 more element
A contact lens solution comprising:
- at least 0.00001 weight percent of a polyhexamethylene biguanide;
- between 0.00001 and 10 weight percent of pantothenic acid or a salt of pantothenic acid that functions as a preservative enhancer;
- a physiologically compatible buffer selected from the group consisting of phosphate, bicarbonate, citrate, borate, ACES, BES, BICINE, BIS, BIS-Tris, BIS-Tris Propane, HEPES, HEPPS, imidazole, MES, MOPS, PIPES, TRIS, TAPS, TES, an amino acid, and Tricine;
- wherein the contact lens solution has a low chloride concentration of less than 0.1 mole percent chloride, and the combination of the polyhexamethylene biguanide, the preservative enhancer, and the low chloride concentration provide an enhanced preservative effect relative to a corresponding contact lens solution having a chloride concentration of more than 0.1 mole percent.
1 more element
Dependencies are inferred from the claim text.