Detection and concentration determination of 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy) propanoic acid by LC/MS/MS
AssigneeSuffolk County Water Authority
InventorAmanda Comando
Life of this patent
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Abstract
A method and system for injecting an unconcentrated sample into a receiving LC/MS/MS system that is configured to determine a concentration of GenX within the unconcentrated sample, wherein the LC/MS/MS includes ESI. The unconcentrated sample is subjected to the following ESI conditions: i) a probe gas temperature of approximately 120° C. to approximately 160° C.; ii) a sheath gas heater setting of approximately 150° C. to approximately 275° C.; and iii) a sheath gas flow of approximately 6 L/min to approximately 11 L/min. The concentration of GenX is determined within the unconcentrated sample, wherein the concentration of GenX within the unconcentrated sample has a minimum reporting level of approximately 0.010 μg/L.
Claims20
A method for detecting GenX in an unconcentrated sample comprising:
- injecting an unconcentrated sample into an LC/MS/MS system that is configured to determine a concentration of GenX within the unconcentrated sample, wherein the LC/MS/MS includes ESI;
- subjecting the unconcentrated sample to the following ESI conditions:
- i) a probe gas temperature of approximately 120° C. to approximately 160° C.;
- ii) a sheath gas heater setting of approximately 150° C. to approximately 275° C.;
- and
- iii) a sheath gas flow of approximately 6 L/min to approximately 11 L/min;
- and
- determining the concentration of GenX within the unconcentrated sample, wherein the concentration of GenX within the unconcentrated sample is at least approximately 0.010 μg/L.
A GenX detection system comprising:
- an LC/MS/MS system operable utilizing ESI and configured to:
- receive an injection of a unconcentrated sample containing GenX;
- subject the unconcentrated sample to the following ESI conditions:
- i) a probe gas temperature of approximately 120° C. to approximately 160° C.;
- ii) a sheath gas heater setting of approximately 150° C. to approximately 275° C.;
- and
- iii) a sheath gas flow of approximately 6 L/min to approximately 11 L/min;
- and
- determine a concentration of GenX within the unconcentrated sample, wherein the concentration of GenX within the unconcentrated sample is at least approximately 0.010 μg/L.
A method for detecting GenX in a solution comprising:
- injecting a solution containing GenX into an LC/MS/MS system that is configured to detect GenX within the solution, wherein the LC/MS/MS includes ESI;
- subjecting a GenX-containing LC eluent of the solution to the following ESI conditions:
- i) a probe gas temperature of approximately 120° C. to approximately 160° C.;
- ii) a sheath gas heater setting of approximately 150° C. to approximately 275° C.;
- and
- iii) a sheath gas flow of approximately 6 L/min to approximately 11 L/min;
- and
- determining a concentration of GenX within the solution containing GenX, wherein an injected amount of GenX within the solution containing GenX is at least approximately 7.5×10−7 μg.
Dependencies are inferred from the claim text.