Dynamic display of multi-parameter quantitative biological data
AssigneeBecton, Dickinson and Company
InventorsOliver Crespo-Diaz, Alexander Fainshtein, Mengxiang Tang
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Abstract
Data visualization features are described that provide a fast and accurate tool for displaying visualizations of high parameter data. The visualization features include graphically representing multiple parameters simultaneously with the associated statistical data for each parameter in an interactive way that maintains the contextual relationships between parameters and the related cell population. The visualization may be dynamically generated based on the measurements for the cell population and the resources available to the display device. The visualization features may be used for displaying high parameter multi-color flow cytometry or genomic data sets.
Claims22
A graphics control device for displaying a representation of multi-parametric data for cells on a graphical user interface, wherein the data for a cell includes respective measurements for a plurality of parameters, the graphics control device comprising:
- an input device port configured to receive, from an input device, a first selection indicating a subset of the cells;
- and
- a plot generator configured to, in response to receiving the first selection:
- dynamically display a base object, wherein at least one of a size or a shape of the base object is identified based at least in part on a size of the subset of the cells, and
- dynamically display respective interactive controls, wherein at least one of a size or a shape of an interactive control is identified based at least in part on measurements for the subset of the cells for one of the plurality of parameters, and wherein each interactive control is displayed at respective points on the base object.
A computer-implemented method for displaying a representation of multi-parametric data for cells on a graphical user interface, wherein the data for a cell includes respective measurements for a plurality of parameters, the computer-implemented method comprising:
- under the control of one or more computing devices:
- receiving, from an input device, a first selection indicating a subset of the cells;
- and
- in response to receiving the first selection:
- dynamically displaying a base object, wherein at least one of a size or a shape of the base object is identified based at least in part on a size of the subset of the cells, and
- dynamically displaying respective interactive controls, wherein at least one of a size or a shape of an interactive control is identified based at least in part on a measurement for a cell in one of the plurality of parameters, and wherein each interactive control is displayed at a point on the base object.
An system for displaying a representation of multiparametric cellular data for cells on a graphical user interface, the system comprising:
- a particle analyzer configured to detect, for each of the cells, measurements for respective markers of a plurality of markers;
- and
- graphics processing circuitry in communication with the particle analyzer, the graphics processing circuitry configured to:
- receive, from an input device, a first selection indicating a subset of the cells, and
- in response to receiving the first selection:
- dynamically display a base object, wherein at least one of a size or a shape of the base object is identified based at least in part on a size of the subset of the cells, and
- dynamically display respective interactive controls, wherein at least one of a size or a shape of an interactive control is identified based at least in part on a measurement for a cell for one of the plurality of markers, and wherein each interactive control is displayed at a respective point on the base object.
Dependencies are inferred from the claim text.