System and method for determining thresholds or a range of values used to allocate patients to a treatment level of a treatment program

A method of facilitating computer-assisted determination of test result thresholds to assign patients to a particular level of treatment for a clinical condition, the method comprising:

• obtaining, by one or more hardware processors, a request for a recommended treatment level for a patient having a clinical condition, the recommended treatment level request including test result values associated with the patient;
• obtaining, by the one or more hardware processors, historical information associated with patients having the clinical condition, the historical information including (i) test result values associated with the patients, (ii) information on treatment levels provided to the patients for the clinical condition, (iii) information on health outcomes of the patients with regard to the clinical condition, the health outcome being measured in terms of one or both of mortality rate or perceived quality of life, and (iv) information on costs associated with providing each of the treatment levels to the patients;
• determining, by the one or more hardware processors, a number of available treatment levels for the clinical condition based on the historical information, the number of available treatment levels specifying how many levels of treatment for the clinical condition are available to be assigned to a given patient;
• determining, by the one or more hardware processors, one or more result value thresholds to be used for assigning a given patient to a particular level of treatment for the clinical condition by:
• responsive to the determined number of available treatment levels being a first number of treatment levels, defining a first set of differential equations for determining the one or more result value thresholds, the first set of differential equations configured to assess net health benefits for a first number of candidate sets of result value thresholds to determine the one or more result value thresholds;
• responsive to the determined number of available treatment levels being a second number of treatment levels greater than the first number of treatment levels, (i) defining a second set of differential equations and (ii) solving the second set of differential equations via a Levenberg-Marquardt algorithm for determining the one or more result value thresholds, the second set of differential equations configured to assess net health benefits for a second number of candidate sets of result value thresholds to determine the one or more result value thresholds, the second number of candidate sets of result value thresholds being different from the first number of candidate sets of result value thresholds, a number of differential equations in the first set of differential equations being different from a number of differential equations in the second set of differential equations;
• and
• using the selected set of differential equations to determine the one or more result value thresholds;
• and
• generating, by the one or more hardware processors, the recommended treatment level for the patient based on the test result values associated with the patient and the one or more result value thresholds.