Back to results
US 10,591,749 B2Granted
Medical device, combination of coating solutions, and method for producing medical device
AssigneeToray Industries, Inc.
InventorsMasataka Nakamura, Rumiko Kitagawa, Ryuta Tamiya
Life of this patent
Estimating the term…
Abstract
Disclosed is a medical device having an elastic modulus of 100 kPa or more and 2,000 kPa or less, a water content of 10% by mass or less, a tensile elongation of 50% or more and 3,000% or less, and a dynamic contact angle (advancing angle) relative to a borate buffer of 80° or less. The present invention can significantly reduce or avoid a phenomenon of adhesion to a surface when contacted with a surface outside or inside the body, which has hitherto been regarded as a problem in a conventional medical device.
Claims9
A medical device having:
- an elastic modulus of 100 kPa or more and 2,000 kPa or less,
- a water content of 5% by mass or less,
- a tensile elongation of 50% or more and 3,000% or less, and
- a dynamic contact angle (advancing angle) relative to a borate buffer of 80° or less, wherein a surface friction coefficient ratio (Qa) in a state of being wetted with a borate buffer is 0.8 or less,
- provided that Qa=MIUa/MIUo:
- where MIUa represents a coefficient of surface friction between the medical device and a smooth quartz glass plate in the state of being wetted with the borate buffer;
- and MIUo is 0.305,
- wherein the medical device includes a base material, and a layer made of an acidic polymer and a basic polymer is formed on at least a part of a surface of the base material,
- at least one of the basic and the acidic polymers comprises a polymer having an amide bond selected from the group consisting of:
- acidic polymers having an amide bond selected from a (meth)acrylic acid/N,N-dimethylacrylamide copolymer and a 2-acrylamido-2-methylpropanesulfonic acid/N,N-dimethylacrylamide copolymer, and
- basic polymers having an amide bond selected from an N,N-dimethylaminoethyl methacrylate/N,N-dimethylacrylamide copolymer and an N,N-dimethylaminopropyl acrylamide/N,N-dimethylacrylamide copolymer;
- and
- wherein the base material contains, as main components, a copolymer of the following components A and B:
- component A:
- a polysiloxane compound which has a plurality of polymerizable functional groups per molecule, and also has a number average molecular weight of 6,000 or more, and
- component B:
- a polymerizable monomer having a fluoroalkyl group.
14 more elements
Dependencies are inferred from the claim text.