Microorganism for simultaneously producing L-amino acid and riboflavin, and method for producing L-amino acid and riboflavin using same

A modified Corynebacterium glutamicum microorganism for simultaneously producing L-lysine or L-threonine, and riboflavin,

• wherein said modified Corynebacterium glutamicum microorganism has enhanced expression of a riboflavin (rib) operon as compared to the expression of a rib operon in a corresponding wild-type Corynebacterium glutamicum microorganism, wherein the rib operon comprises genes encoding riboflavin biosynthesis enzymes, and wherein the expression of the rib operon in said modified Corynebacterium glutamicum microorganism is enhanced by increasing intracellular copy number of the genes of the rib operon, replacing the native promoter of the rib operon with a stronger promoter, and a combination thereof,
• wherein said modified Corynebacterium glutamicum microorganism has increased L-lysine or L-threonine-producing ability as compared to a corresponding wild-type Corynebacterium glutamicum microorganism, and
• wherein the concentration of riboflavin produced by said modified Corynebacterium glutamicum microorganism is increased by 56 to 73-fold as compared to the concentration of riboflavin produced by a corresponding wild-type Corynebacterium glutamicum microorganism under the same conditions, while maintaining the increased production of L-lysine or L-threonine as compared to a corresponding wild-type Corynebacterium glutamicum microorganism.