Therapeutic oligonucleotides
AssigneeCaris Science, Inc.
InventorsHeather O'Neill, Mark Miglarese, David Spetzler
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Abstract
Methods and compositions are provided for oligonucleotides that bind targets of interest. The targets include cells and microvesicles, such as those derived from various diseases. The oligonucleotides can be used for diagnostic and therapeutic purposes. The target of the oligonucleotides can be a therapeutic target such as Complement Component 1, Q Subcomponent (C1q) or a subunit thereof.
Claims19
An oligonucleotide comprising a sequence that is at least 95 percent identical to the full length of an oligonucleotide sequence selected from anyone of SEQ ID NOs. 1472, 1475, 1477, 1482, and 4152-4157, and binds C1q.
Dependencies are inferred from the claim text.