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US 10,590,408 B2Granted
Method and composition for biomolecule stabilization
AssigneeGe Healthcare UK Limited
InventorsPeter James Tatnell, Elizabeth Mary Ashman
Life of this patent
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Abstract
The present invention relates to biomolecule stabilization to provide biomolecules, such as sensitive polymerases, in a convenient ready-to-go format. The invention provides a method and composition in which non-ionic surfactant or detergents of the polyoxyethylene cetyl ether family are used, preferably a Brij reagent or a combination of Brij reagents.
Claims9
A method for stabilizing biomolecules, comprising:
- treating a biomolecule with a lyophilisation mixture comprising non-ionic surfactant Brij-58 (polyoxyethylene-20-cetyl ether);
- dispensing said mixture into a receptacle;
- and freeze-drying said mixture.
A stabilized biomolecule composition, comprising a biomolecule stabilized in a mixture comprising non-ionic surfactant Brij 58 (polyoxyethylene-20-cetyl ether).
Dependencies are inferred from the claim text.