Antibody

An antibody which comprises a variable heavy (VH) chain comprising CDR1, CDR2 and CDR3, and a variable light (VL) chain comprising CDR1, CDR2 and CDR3, wherein the VH-CDR1 amino acid sequence is GGTFSSYA (SEQ ID NO:

• 106), wherein the VH-CDR2 amino acid sequence is IIPIFGTA (SEQ ID NO:
• 108), wherein the VH-CDR 3 amino acid sequence is VRITIFGVVMVKSDNWFDP (SEQ ID NO:
• 306), wherein the VL-CDR1 amino acid sequence is QSVSSN (SEQ ID NO:
• 549), wherein the VL-CDR2 amino acid sequence is GAS, and wherein the VL-CDR3 amino acid sequence is QQYNNLYT (SEQ ID NO:
• 715);
• wherein the antibody is selected from the group consisting of a recombinant full-length antibody comprising the VH and VL chains from one species and a constant domain from a different species;
• a recombinant functional antibody fragment, wherein the VH chain and VL chain are joined by a polypeptide linker;
• a chimeric antibody;
• a bispecific antibody;
• a minibody;
• and an antibody fusion, wherein the antibody is conjugated to a non-antibody molecule.