Process for a preparation of the modified porcine plasma fibronectin for enhance wound healing
AssigneeNational Yang-Ming University
InventorJean-Cheng Kuo
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Abstract
This invention reveals the potential applications of modified porcine plasma fibronectin that could be applied as a safe material for clinical wound healing and tissue repair. In order to seek safe sources of plasma fibronectin for practical consideration in wound dressing, this invention isolated and modified fibronectin from porcine plasma and demonstrated that modified porcine plasma fibronectin has similar ability as homo plasma fibronectin being as a suitable substrate for stimulation of cell adhesion and directed cell migration. The present invention also reveals a material and a pharmaceutical composition enhance wound healing.
Claims8
A method for enhanced wound healing in a subject, wherein the method comprises:
- a) treating porcine fibronectin with an enzyme that modifies the glycans attached to the fibronectin protein, thereby producing a porcine fibronectin with modified glycans;
- and
- b) administering the porcine fibronectin with modified glycans to the subject.
Dependencies are inferred from the claim text.