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US 10,589,273 B2Granted
Cationic polymers and method of surface application
AssigneeIllumina, Inc.
InventorsAllen E Eckhardt, Rigo Pantoja, Sean M Ramirez, Petr Capek, Edwin Li
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Abstract
Embodiments of present application are directed to microfluidic devices and particularly digital micro-plastic fluidic devices that are specifically designed to prevent sample contamination during sample processing, methods of manufacturing the same, and methods to improve sample analysis process by preventing sample contamination.
Claims19
A microfluidic device comprising:
- a surface of the microfluidic device;
- a conductive coating layer comprising one or more polymers, including an anionic polymer;
- a passivation layer comprising a cationic compound;
- one or more hydrophobic coating layers;
- and
- one or more microchannels, microtracks or micropaths;
- wherein the passivation layer is immediately adjacent to the conductive coating layer and in between the conductive coating layer and one hydrophobic coating layer, wherein the passivation layer comprises a water-insoluble material, and wherein the water-insoluble material comprises a charge complex of the anionic polymer of the conducting coating layer with the cationic compound.
4 more elements
Dependencies are inferred from the claim text.