Systems and methods for network based neurostimulation of cognitive processes

A method of enhancing a cognitive process in a subject having a disease or neurological injury, the method comprising applying an intracranial electrical stimulation to a plurality of nodes in different regions of the brain of the subject, wherein the intracranial electrical stimulation is applied at nodes in different regions of the brain of the subject that are active during an effective cognitive process, wherein:

• the different regions of the brain of the subject comprise a first region of the brain in a hippocampus (HPC) region, a second region of the brain in a parahippocampal (PHG) region, and a third region of the brain in a prefrontal cortex (PFC) region;
• and
• applying the intracranial electrical simulation to the plurality of nodes comprises:
• applying a first electrical signal to a first node in the first region of the brain;
• applying a second electrical signal to a second node in the second region of the brain;
• applying a third electrical signal to a third node in the third region of the brain;
• and
• inducing coherent oscillations between the first, second and third nodes.