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US 10,588,985 B2Granted
Compositions and methods relating to RAD6 inhibition
AssigneeWayne State University
InventorsMalathy Shekhar, Guangzhao Mao, Yanhua Zhang
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Abstract
Pharmaceutical compositions, methods of treatment of proliferative diseases and commercial packages are provided according to aspects of the present invention which relate to a first therapeutic agent coupled to a nanoparticle, wherein the first therapeutic agent is SMI #8 or SMI #9 a pharmaceutically acceptable salt, ester, amide, stereoisomer, hydrate, or derivative of either thereof. According to particular aspects, the SMI #8 or SMI #9 is conjugated to gold nanoparticles.
Claims17
A pharmaceutical composition, comprising:
- or a pharmaceutically acceptable salt of either thereof.
A commercial package, comprising:
- or a pharmaceutically acceptable salt of either thereof.
Dependencies are inferred from the claim text.