Carbohydrate-glycolipid conjugate vaccines

Compound of the general formula (XIV):

• Wherein:
• A represents a carbohydrate antigen selected from the group consisting of a bacterial capsular saccharide, a saccharide of a viral glycoprotein, a saccharide antigen of sporozoa or parasites, a saccharide antigen of pathogenic fungi, and a saccharide antigen which is specific to cancer cells, and has a number u of 1 to 10,000 of carbohydrate monomers,
• p is the number of residues
• which are bound to the carbohydrate antigen A, and
• p is an integer defined as follows:
• p is 1 or 2 if u is 1
• p is 1, 2, 3 or 4 if u is 2
• p is 1, 2, 3, 4, 5 or 6 if u is 3
• p is 1, 2, 3, 4, 5, 6, 7 or 8 if u is 4
• 1≤p≤10 if 5≤u≤10
• 2≤p≤50 if 11≤u≤100
• 20≤p≤200 if 101≤u≤1000
• 50≤p≤400 if 1001≤u≤10000
• L represents -L1-L2-, -L2-, -L2-L3- or -L1-L2-L3-;
• L1 represents one of the following residues:
• wherein x is an integer from 1 to 60;
• Y represents a bond, —NH—, —O—, —S—;
• —S—S—;
• L2 represents —CH2—, —C2H4—, —C3H6—, —C4H8—, —C5H10—, —C6H12—, —C7H14—, —C8H16—, —C9H18—, —C10H20—, —CH(CH3)—, —C[(CH3)2]—, —CH2—CH(CH3)—, —CH(CH3)—CH2—, —CH(CH3)—C2H4—, —CH2—CH(CH3)—CH2—, —C2H4—CH(CH3)—, —CH2—C[(CH3)2]—, —C[(CH3)2]—CH2—, —CH(CH3)—CH(CH3)—, —C[(C2H5)(CH3)]—, —CH(C3H7)—, —(CH2—CH2—O)n—CH2—CH2—, —CO—CH2—, —CO—C2H4—, —CO—C3H6—, —CO—C4H8—, —CO—C5H10—, —CO—C6H12—, —CO—C7H14—, —CO—C9H16—, —CO—C9H18—, —CO—C10H20—, —CO—CH(CH3)—, —CO—C[(CH3)2]—, —CO—CH2—CH(CH3)—, —CO—CH(CH3)—CH2—, —CO—CH(CH3)—C2H4—, —CO—CH2—CH(CH3)—CH2—, —CO—C2H4—CH(CH3)—, —CO—CH2—C[(CH3)2]—, —CO—C[(CH3)2]—CH2—, —CO—CH(CH3)—CH(CH3)—, —CO—C[(C2H5)(CH3)]—, —CO—CH(C3H7)—, —Oβ—(CH2—CH2—O)n—CH2—CH2—;
• n represents an integer from 1 to 60;
• L3 represents —CO—, —O—CO—, —NH—CO—, —NH(C═NH)—, —SO2—, —O—SO2—, —NH—, —NH—CO—CH2—;
• R* and R# represent independently of each other a linear or branched or cyclic, substituted or unsubstituted, saturated or unsaturated carbon residue consisting of 1 to 30 carbon atoms.