Avian reovirus vaccines
AssigneeUniversity of Georgia Research Foundations, Inc.
InventorHolly S. Sellers
Life of this patent
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Abstract
The present invention relates to novel strains of avian reovirus that were isolated from clinical cases of viral arthritis/tenosynovitis in chickens in the southeast United States. The invention is directed to these novel group 1 and group 2 avian reoviruses, diagnostic assays using antibodies and/or nucleotide- or amino acid-specific components of such viruses, such as the S1 gene encoding the sigma C protein, and to vaccines that protect chickens from disease caused by such viruses.
Claims21
An isolated avian reovirus, wherein the avian reovirus is attenuated by at least 25 passages in an egg or a host cell line and wherein the avian reovirus comprises a sigma C protein comprising an amino acid sequence with at least about 98% sequence identity to SEQ ID NO:6.
An isolated avian reovirus, wherein the avian reovirus comprises the avian reovirus strain 96139 deposited at the ATCC under Patent Designation PTA-125688 attenuated by at least 125 passages in an egg or a host cell line.
Dependencies are inferred from the claim text.