Peptide for promoting bone formation or inhibiting bone resorption and use thereof
AssigneeSeoul National University R&Db Foundation
InventorByung Moo Min
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Abstract
The present invention relates to a peptide for promoting bone formation or inhibiting bone resorption and use thereof. The peptide for regulating bone formation or bone resorption of the present invention has the effect of promoting bone formation by enhancing osteoblast differentiation and concurrently inhibiting bone resorption by restricting osteoclast differentiation and resorptive function. Additionally, due to the low molecular weight, the peptide can be economically produced, and is thus useful for preventing and treating bone diseases.
Claims11
A method for treating bone disease, the method comprising:
- administering a pharmaceutical composition comprising a peptide for regulating bone formation or bone resorption, which consists of 12 to 173 continuous amino acids within the amino acid sequence of SEQ ID NO:
- 19 and comprises the amino acid sequence (RVYFFKGKQYWE) of SEQ ID NO:
- 17, to a subject having bone disease and in need of promoting bone formation or inhibiting bone resorption.
A method for treating bone disease, the method comprising:
- administering a pharmaceutical composition comprising a peptide for regulating bone formation or bone resorption, which consists of the amino acid sequence (RVYFFKGKQYWE) of SEQ ID NO:
- 17, to a subject having bone disease and in need of promoting bone formation or inhibiting bone resorption.
Dependencies are inferred from the claim text.