Use of angiopoietins in promoting blood coagulation and in the treatment of blood coagulation disorders
AssigneeRegeneron Pharmaceuticals, Inc.
InventorsChristopher Daly, Samuel Davis
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Abstract
The present invention provides methods for promoting blood coagulation and/or treating blood coagulation disorders in a subject in need thereof. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising an angiopoietin protein or a modified angiopoietin protein molecule such as AngF1-Fc-F1 or AngF2-Fc-F2.
Claims15
A method of treating, preventing or ameliorating at least one symptom, indication or complication of a blood coagulation disorder, comprising administering to a subject in need thereof a pharmaceutical composition comprising a therapeutically effective amount of a fusion protein comprising angiopoietin-1 or a portion thereof fused to an immunoglobulin Fc fragment, and a pharmaceutically acceptable carrier, wherein the pharmaceutical composition stimulates blood coagulation in the subject.
Dependencies are inferred from the claim text.