Compositions comprising triterpenoids
AssigneeRegenera Pharma Ltd.
InventorsZadik Hazan, Konstantin Adamsky, Andre C. B. Lucassen, Nurit Novak
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Abstract
The invention relates to compositions and formulations comprising at least one triterpenoic acid and at least one neutral triterpenoid and uses thereof for treating for use in treating a condition selected from Alzheimer's disease (AD), Parkinson's Diseases (PD) and vascular dementia (VD).
Claims21
A method of treating a condition selected from Multi System Atrophy (MSA), Progressive Supranuclear Palsy (PSP), Parkinson-plus syndrome, Parkinsonisms, tauopathic diseases and conditions and Pick's disease, comprising administering to a subject in need thereof a pharmaceutical composition comprising a combination of at least one triterpenoic acid and at least one neutral triterpenoid, and a pharmaceutically acceptable carrier, wherein the triterpenoic acid is selected from masticadienonic acid (MDA), isomasticadienonic acid (IMDA) or both, wherein the neutral triterpenoid is selected from (8R)-3-beta-8-dihydroxypolypoda-13 E,17E,21-triene (NF-1), (8R)-3-Oxo-8-hydroxypolypoda-13E,17E,21-triene (NF-2) or both.
Dependencies are inferred from the claim text.