Back to results
US 10,588,907 B2Granted
Methods and compositions for inhibiting the interaction of menin with MLL proteins
AssigneesKura Oncology, Inc., The Regents of the University of Michigan
InventorsJolanta Grembecka, Tomasz Cierpicki, Dmitry Borkin, Jonathan Pollock, Liansheng Li, Tao Wu, Jun Feng, Pingda Ren, Yi Liu
Life of this patent
Estimating the term…
Abstract
The present disclosure provides compositions and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins. The compositions and methods of use are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, and/or menin.
Claims1
A compound selected from the group consisting of:
Dependencies are inferred from the claim text.